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masque wrote (edited )

Possibly a silly question: in order to measure the specificity & sensitivity of the test, how do they find the ground truth about which patients do or don't have the antibodies prior to the development of the test for antibodies? I guess you could use a slower but more reliable test, but is there then some sort of chicken & egg problem?

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celebratedrecluse wrote

an interesting epistemology question, which I am not qualified to answer. Perhaps someone else can chime in with more information and knowledge of this field, I would be very interested to learn about it

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