I think the argument that our rejection of civilization would be terrible for trans people is based in colonial and (ironically) very transphobic attitudes. Indigenous and so-called “primitive” cultures around the world have always had gender-variant people and non-binary gender categories. (I don’t refer to them as trans because they were simply considered to be their gender, without any modifier.) To imply that trans people would suffer without western-style civilization and tech devalues those lived experiences.
Further, the notion that trans people need medicine or surgery to transition or to pass or for whatever reason is very alienating to a lot of trans people.